Summary:

Customers may have a query regarding installing CRM on an existing web server, where another application is installed on the default web site.

More information:

By default, Sage CRM will install to a virtual directory under the default website. If you need it to be on a website other than the default, you can move the CRM and SDATA virtual directories from one website to another after installation.

Strictly speaking, this is not the recommended configuration, but moving CRM to another website should work fine so long as the virtual directories are moved, and it is ensured that the bindings are set up on the new website.